Quantitative Systems Biology Studies Reveal a Nested Relay Mechanism for TGF-Beta Signaling
نویسندگان
چکیده
منابع مشابه
Cells interpret temporal information from TGF - β through a 1 nested relay mechanism
11 The detection and transmission of the strength and temporal quality of intracellular and 12 extracellullar signals is an essential cellular mechanism. While TGF-β signaling is one of the 13 most thoroughly studied signaling pathways, the mechanisms by which cells translate TGF-β 14 signals remain unclear. In this paper, through an integrated quantitative and computational 15 approach we demo...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2017
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2016.11.243